Structure of PDB 1doa Chain B

Receptor sequence
>1doaB (length=200) Species: 9913 (Bos taurus) [Search protein sequence]
EPTAEQLAQIAAENEEDEHSVNYKPPAQKSIQEIQELDKDDESLRKYKEA
LLGRVAVSADPNVPNVVVTRLTLVCSTAPGPLELDLTGDLESFKKQSFVL
KEGVEYRIKISFRVNREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAE
EYEFLTPMEEAPKGMLARGSYNIKSRFTDDDRTDHLSWEWNLTIKKEWKD
3D structure
PDB1doa Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI.
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GER B Q130 W194 Q126 W190
Gene Ontology
Molecular Function
GO:0005094 Rho GDP-dissociation inhibitor activity
GO:0005096 GTPase activator activity
Biological Process
GO:0007266 Rho protein signal transduction
GO:0071526 semaphorin-plexin signaling pathway
Cellular Component
GO:0001772 immunological synapse
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1doa, PDBe:1doa, PDBj:1doa
PDBsum1doa
PubMed10676816
UniProtP19803|GDIR1_BOVIN Rho GDP-dissociation inhibitor 1 (Gene Name=ARHGDIA)

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