Structure of PDB 1dks Chain B

Receptor sequence

>1dksB (length=73) Species: 9606 (Homo sapiens) [Search protein sequence]

KQIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQG
WVHYMIHEPEPHILLFRRPLPKK

3D structure

PDB

1dks Crystal structure of the human cell cycle protein CksHs1: single domain fold with similarity to kinase N-lobe domain.

Chain

Resolution

3.2 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	PO4	B	R20 Q50 S51 W54	R17 Q47 S48 W51

Gene Ontology

	Molecular Function
GO:0005515	protein binding
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
GO:0019901	protein kinase binding
GO:0042393	histone binding
GO:0043130	ubiquitin binding
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription
GO:0007346	regulation of mitotic cell cycle
GO:0044772	mitotic cell cycle phase transition
GO:0048144	fibroblast proliferation
GO:0051301	cell division

	Cellular Component
GO:0000307	cyclin-dependent protein kinase holoenzyme complex
GO:0005654	nucleoplasm
GO:0019005	SCF ubiquitin ligase complex

External links

PDB	RCSB:1dks, PDBe:1dks, PDBj:1dks
PDBsum	1dks
PubMed	7791211
UniProt	P61024\|CKS1_HUMAN Cyclin-dependent kinases regulatory subunit 1 (Gene Name=CKS1B)