Structure of PDB 1dkf Chain B

Receptor sequence
>1dkfB (length=232) Species: 9606 (Homo sapiens) [Search protein sequence]
PEVGELIEKVRKAHQETFPALCQLGKYTTSEQRVSLDIDLWDKFSELSTK
CIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTM
TFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICL
ICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDL
RSISAKGAERVITLKMEIPGSMPPLIQEMLEN
3D structure
PDB1dkf Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMS B F228 S229 L231 S232 T233 C235 L269 I273 F286 S287 F302 G391 M406 F44 S45 L47 S48 T49 C51 L85 I89 F102 S103 F118 G207 M222
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0048384 retinoic acid receptor signaling pathway
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1dkf, PDBe:1dkf, PDBj:1dkf
PDBsum1dkf
PubMed10882070
UniProtP10276|RARA_HUMAN Retinoic acid receptor alpha (Gene Name=RARA)

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