Structure of PDB 1d4w Chain B

Receptor sequence
>1d4wB (length=102) Species: 9606 (Homo sapiens) [Search protein sequence]
AVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIY
TYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPV
EK
3D structure
PDB1d4w Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R13 E17 R32 S34 E35 S36 C42 Y50 I51 T53 Y54 R55 E67 T68 A69 V72 R75 D91 G93 R11 E15 R30 S32 E33 S34 C40 Y48 I49 T51 Y52 R53 E65 T66 A67 V70 R73 D89 G91
Gene Ontology
Biological Process
GO:0006968 cellular defense response
GO:0007267 cell-cell signaling
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:1d4w, PDBe:1d4w, PDBj:1d4w
PDBsum1d4w
PubMed10549287
UniProtO60880|SH21A_HUMAN SH2 domain-containing protein 1A (Gene Name=SH2D1A)

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