Structure of PDB 1crx Chain B

Receptor sequence

>1crxB (length=322) Species: 10678 (Punavirus P1) [Search protein sequence]

SDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEPE
DVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMRR
IRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAYN
TLLRIAEIARIRVKDISRTDGGRMLIHIGRTKTLVSTAGVEKALSLGVTK
LVERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEATH
RLIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNVN
IVMNYIRNLDSETGAMVRLLED

3D structure

PDB

1crx Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse.

Chain

Resolution

2.4 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	B	M44 S47 R50 R81 L83 A84 K86 T87 Q90 A131 K132 Q156 R159 K201 R241 V242 K244 L256 S257 R259 R282 Y324 R326	M25 S28 R31 R62 L64 A65 K67 T68 Q71 A112 K113 Q137 R140 K182 R222 V223 K225 L237 S238 R240 R263 Y305 R307
BS02	dna	B	R118 K122	R99 K103
BS03	dna	B	F37 S38 H40 T41 R100 R101 R121 I174 A175 K201 R243 K244 N245 R259 E262 R282 Y283 S287 G288 H289	F18 S19 H21 T22 R81 R82 R102 I155 A156 K182 R224 K225 N226 R240 E243 R263 Y264 S268 G269 H270

Gene Ontology

	Molecular Function
GO:0003677	DNA binding

	Biological Process
GO:0006310	DNA recombination
GO:0015074	DNA integration

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:1crx, PDBe:1crx, PDBj:1crx
PDBsum	1crx
PubMed	9288963
UniProt	P06956\|RECR_BPP1 Recombinase cre (Gene Name=cre)

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