Structure of PDB 1c9k Chain B

Receptor sequence
>1c9kB (length=180) [Search protein sequence]
MILVTGGARSGKSRHAEALIGDAPQVLYIATSQILDDEMAARIQHHKDGR
PAHWRTAECWRHLDTLITADLAPDDAILLECITTMVTNLLFALGGENDPE
QWDYAAMERAIDDEIQILIAACQRCPAKVVLVTNEVGMGIVPENRLARHF
RDIAGRVNQRLAAAADEVWLVVSGIGVKIK
3D structure
PDB1c9k Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase (CobU) complexed with GMP: evidence for a substrate-induced transferase active site.
ChainB
Resolution2.2 Å
3D
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Enzymatic activity
Enzyme Commision number 2.7.1.156: adenosylcobinamide kinase.
2.7.7.62: adenosylcobinamide-phosphate guanylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5GP B Y28 A30 S32 I43 H46 R50 E58 E80 Y28 A30 S32 I43 H46 R50 E58 E80
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0008820 cobinamide phosphate guanylyltransferase activity
GO:0016301 kinase activity
GO:0043752 adenosylcobinamide kinase activity
Biological Process
GO:0009236 cobalamin biosynthetic process
GO:0016310 phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1c9k, PDBe:1c9k, PDBj:1c9k
PDBsum1c9k
PubMed10529169
UniProtQ05599|COBU_SALTY Bifunctional adenosylcobalamin biosynthesis protein CobU (Gene Name=cobU)

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