Structure of PDB 1c39 Chain B

Receptor sequence
>1c39B (length=152) Species: 9913 (Bos taurus) [Search protein sequence]
EKTCDLVGEKGKESEKELALLKRLTPLFQKSFESTVGQSPDMYSYVFRVC
REAGQHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEY
DNHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLA
CS
3D structure
PDB1c39 Structural basis for recognition of phosphorylated high mannose oligosaccharides by the cation-dependent mannose 6-phosphate receptor.
ChainB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN B D43 Y45 Q68 D41 Y43 Q66
BS02 M6P B Y45 Q66 Y102 D103 N104 H105 R111 E133 R135 Y143 Y43 Q64 Y100 D101 N102 H103 R109 E131 R133 Y141
Gene Ontology
Molecular Function
GO:0019904 protein domain specific binding
Biological Process
GO:0006622 protein targeting to lysosome
Cellular Component
GO:0005768 endosome
GO:0005794 Golgi apparatus

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Cellular Component
External links
PDB RCSB:1c39, PDBe:1c39, PDBj:1c39
PDBsum1c39
PubMed10514470
UniProtP11456|MPRD_BOVIN Cation-dependent mannose-6-phosphate receptor (Gene Name=M6PR)

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