Structure of PDB 1bsx Chain B

Receptor sequence
>1bsxB (length=243) Species: 9606 (Homo sapiens) [Search protein sequence]
KPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPKVDLEA
FSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAA
VRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDT
EVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFW
PKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
3D structure
PDB1bsx Structure and specificity of nuclear receptor-coactivator interactions.
ChainB
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B V284 K288 I302 E457 V66 K70 I84 E239
BS02 T3 B F272 I276 S314 L330 N331 L346 H435 M442 F54 I58 S96 L112 N113 L128 H217 M224
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1bsx, PDBe:1bsx, PDBj:1bsx
PDBsum1bsx
PubMed9808622
UniProtP10828|THB_HUMAN Thyroid hormone receptor beta (Gene Name=THRB)

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