Structure of PDB 1bk6 Chain B

Receptor sequence
>1bk6B (length=422) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
LPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEF
MRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVE
VKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWT
LSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGP
QEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVI
NAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPL
VKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLE
IADNRIIEVTLDALENIIKMGEADKEARGLNINENADFIEKAGGMEKIFN
CQQNENDKIYEKAYKIIETYFG
3D structure
PDB1bk6 Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R117 P121 W153 N157 S160 Q192 W195 N199 D203 W237 N241 R29 P33 W65 N69 S72 Q104 W107 N111 D115 W149 N153
BS02 peptide B V327 G329 N367 W405 V239 G241 N279 W317
External links
PDB RCSB:1bk6, PDBe:1bk6, PDBj:1bk6
PDBsum1bk6
PubMed9695948
UniProtQ02821|IMA1_YEAST Importin subunit alpha (Gene Name=SRP1)

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