Structure of PDB 1b8g Chain B

Receptor sequence
>1b8gB (length=425) Species: 3750 (Malus domestica) [Search protein sequence]
MLSRNATFNSSSYFLGWQEYEKNPYHEVHNTNGIIQMGLAENQLCFDLLE
SWLAKNPEAAAFKKNGESIFAELALFQDYHGLPAFKKAMVDFMAEIRGNK
VTFDPNHLVLTAGATSANETFIFCLADPGEAVLIPTPYYPGFDRDLKWRT
GVEIVPIHCTSSNGFQITETALEEAYQEAEKRNLRVKGVLVTNPSNPLGT
TMTRNELYLLLSFVEDKGIHLISDEIYSGTAFSSPSFISVMEVLKDRNCD
ENSEVWQRVHVVYSLSKDLGLPGFRVGAIYSNDDMVVAAATKMSSFGLVS
SQTQHLLSAMLSDKKLTKNYIAENHKRLKQRQKKLVSGLQKSGISCLNGN
AGLFCWVDMRHLLRSNTFEAEMELWKKIVYEVHLNISPGSSCHCTEPGWF
RVCFANLPERTLDLAMQRLKAFVGE
3D structure
PDB1b8g Structure of 1-aminocyclopropane-1-carboxylate synthase, a key enzyme in the biosynthesis of the plant hormone ethylene.
ChainB
Resolution2.37 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y145 D230 I232 K273
Catalytic site (residue number reindexed from 1) Y139 D224 I226 K267
Enzyme Commision number 1.4.-.-
4.4.1.14: 1-aminocyclopropane-1-carboxylate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP B G119 A120 T121 Y145 I232 Y233 S270 S272 K273 R281 G113 A114 T115 Y139 I226 Y227 S264 S266 K267 R275
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008483 transaminase activity
GO:0016491 oxidoreductase activity
GO:0016829 lyase activity
GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006520 amino acid metabolic process
GO:0009058 biosynthetic process
GO:0009693 ethylene biosynthetic process
GO:0009835 fruit ripening
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1b8g, PDBe:1b8g, PDBj:1b8g
PDBsum1b8g
PubMed10610793
UniProtP37821|1A1C_MALDO 1-aminocyclopropane-1-carboxylate synthase (Gene Name=ACS-1)

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