Structure of PDB 1b5e Chain B

Receptor sequence
>1b5eB (length=241) Species: 10665 (Tequatrovirus T4) [Search protein sequence]
MISDSMTVEEIRLHLGLALKEKDFVVDKTGVKTIEIIGASFVADEPFIFG
ALNDEYIQRELEWYKSKSLFVKDIPGETPKIWQQVASSKGEINSNYGWAI
WSEDNYAQYDMCLAELGQNPDSRRGIMIYTRPSMQFDYNKDGMSDFMCTN
TVQYLIRDKKINAVVNMRSNDVVFGFRNDYAWQKYVLDKLVSDLNAGDST
RQYKAGSIIWNVGSLHVYSRHFYLVDHWWKTGETHISKKDY
3D structure
PDB1b5e Crystal structure of deoxycytidylate hydroxymethylase from bacteriophage T4, a component of the deoxyribonucleoside triphosphate-synthesizing complex.
ChainB
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E60 C148 D179
Catalytic site (residue number reindexed from 1) E60 C148 D179
Enzyme Commision number 2.1.2.8: deoxycytidylate 5-hydroxymethyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 DCM B R123 R124 R123 R124
BS02 DCM B K28 Y96 C148 R168 S169 N170 D171 D179 H216 Y218 K28 Y96 C148 R168 S169 N170 D171 D179 H216 Y218
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0047153 deoxycytidylate 5-hydroxymethyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:1b5e, PDBe:1b5e, PDBj:1b5e
PDBsum1b5e
PubMed10064578
UniProtP08773|DCHM_BPT4 Deoxycytidylate 5-hydroxymethyltransferase (Gene Name=42)

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