Structure of PDB 1b2a Chain B

Receptor sequence

>1b2aB (length=30) Species: 9823 (Sus scrofa)

FVNQHLCGSHLVEALYLVCGERGFFYTPKA

3D structure

• PDB: 1b2a Crystallographic titration of cubic insulin crystals: pH affects GluB13 switching and sulfate binding.
• Chain: B
• Resolution: 1.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	V2 N3 Q4 H5 L6 C7 L15 V18 C19 R22 G23 F24 F25 A30	V2 N3 Q4 H5 L6 C7 L15 V18 C19 R22 G23 F24 F25 A30

Gene Ontology

Molecular Function

• GO:0005179 hormone activity

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:1b2a, PDBe:1b2a, PDBj:1b2a
• PDBsum: 1b2a
• PubMed: 12657786
• UniProt: P01315|INS_PIG Insulin (Gene Name=INS)