Structure of PDB 1aya Chain B

Receptor sequence
>1ayaB (length=101) Species: 10090 (Mus musculus) [Search protein sequence]
MRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVT
HIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPL
N
3D structure
PDB1aya Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
ChainB
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B E17 R32 S34 K35 S36 T42 T52 H53 L88 K89 E15 R30 S32 K33 S34 T40 T50 H51 L86 K87
External links
PDB RCSB:1aya, PDBe:1aya, PDBj:1aya
PDBsum1aya
PubMed7521735
UniProtP35235|PTN11_MOUSE Tyrosine-protein phosphatase non-receptor type 11 (Gene Name=Ptpn11)

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