Structure of PDB 1axm Chain B

Receptor sequence
>1axmB (length=127) Species: 9606 (Homo sapiens) [Search protein sequence]
PKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTE
TGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVG
LKKNGSCKRGPRTHYGQKAILFLPLPV
3D structure
PDB1axm Structure of a heparin-linked biologically active dimer of fibroblast growth factor.
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SGN B K113 N114 K103 N104
BS02 IDS B N18 K112 K113 K118 N8 K102 K103 K108
BS03 SGN B Q127 K128 A129 Q117 K118 A119
Gene Ontology
Molecular Function
GO:0008083 growth factor activity

View graph for
Molecular Function
External links
PDB RCSB:1axm, PDBe:1axm, PDBj:1axm
PDBsum1axm
PubMed9655399
UniProtP05230|FGF1_HUMAN Fibroblast growth factor 1 (Gene Name=FGF1)

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