Structure of PDB 1aqc Chain B

Receptor sequence
>1aqcB (length=122) Species: 9606 (Homo sapiens) [Search protein sequence]
IIFAANYLGSTQLLNVRMMQAQEAVSRIKMAQKLATEVDLFILTQRIKVL
NADTQETMMDHPLRTISYIADIGNIVVLMARRRYKMICHVFESEDAQLIA
QSIGQAFSVAYQEFLRANGINP
3D structure
PDB1aqc Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B R414 T415 I416 S417 Y418 I419 R431 A472 F479 Y483 F486 R64 T65 I66 S67 Y68 I69 R81 A100 F107 Y111 F114
External links
PDB RCSB:1aqc, PDBe:1aqc, PDBj:1aqc
PDBsum1aqc
PubMed9321393
UniProtQ02410|APBA1_HUMAN Amyloid-beta A4 precursor protein-binding family A member 1 (Gene Name=APBA1)

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