Structure of PDB 1apz Chain B

Receptor sequence
>1apzB (length=141) Species: 9606 (Homo sapiens) [Search protein sequence]
TIGMVVIHKTGHIAAGTSTNGIKFKIHGRVGDSPIPGAGAYADDTAGAAA
ATGNGDILMRFLPSYQAVEYMRRGEDPTIACQKVISRIQKHFPEFFGAVI
CANVTGSYGAACNKLSTFTQFSFMVYNSEKNQPTEEKVDCI
3D structure
PDB1apz Three-dimensional structure of human lysosomal aspartylglucosaminidase.
ChainB
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) T183 T201 R211 T234 G235
Catalytic site (residue number reindexed from 1) T1 T19 R29 T52 G53
Enzyme Commision number 3.5.1.26: N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ASP B T183 R211 D214 T234 G235 G237 T1 R29 D32 T52 G53 G55 BindingDB: Ki=600000nM
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:1apz, PDBe:1apz, PDBj:1apz
PDBsum1apz
PubMed8846222
UniProtP20933|ASPG_HUMAN N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase (Gene Name=AGA)

[Back to BioLiP]