Structure of PDB 1a6e Chain B

Receptor sequence
>1a6eB (length=502) Species: 2303 (Thermoplasma acidophilum) [Search protein sequence]
KDAMKENIEAAIAISNSVRSSLGPRGMDKMLVDSLGDIVITNDGVTILKE
MDVEHPAAKMMVEVSKTQDSFVGDGTTTAVIIAGGLLQQAQGLINQNVHP
TVISEGYRMASEEAKRVIDEISTKIGADEKALLLKMAQTSLNSKSASVAK
DKLAEISYEAVKSVAELRDGKYYVDFDNIQVVKKQGGAIDDTQLINGIIV
DKEKVHPGMPDVVKDAKIALLDAPLEIKKPEFDTNLRIEDPSMIQKFLAQ
EENMLREMVDKIKSVGANVVITQKGIDDMAQHYLSRAGIYAVRRVKKSDM
DKLAKATGASIVSTIDEISSSDLGTAERVEQVKVGEDYMTFVTGCKNPKA
VSILVRGETEHVVDEMERSITDSLHVVASALEDGAYAAGGGATAAEIAFR
LRSYAQKIGGRQQLAIEKFADAIEEIPRALAENAGLDPIDILLKLRAEHA
KGNKTYGINVFTGEIEDMVKNGVIEPIRVGKQAIESATEAAIMILRIDDV
IA
3D structure
PDB1a6e Crystal structure of the thermosome, the archaeal chaperonin and homolog of CCT.
ChainB
Resolution3.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D62 T95 T96 D391
Catalytic site (residue number reindexed from 1) D43 T76 T77 D372
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B L41 G42 P43 D93 G94 T96 T97 T158 S162 G409 L449 V479 V492 L22 G23 P24 D74 G75 T77 T78 T139 S143 G390 L430 V460 V473
BS02 AF3 B N61 T95 T96 N42 T76 T77
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:1a6e, PDBe:1a6e, PDBj:1a6e
PDBsum1a6e
PubMed9546398
UniProtP48425|THSB_THEAC Thermosome subunit beta (Gene Name=thsB)

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