Structure of PDB 1a6a Chain B

Receptor sequence
>1a6aB (length=187) Species: 9606 (Homo sapiens) [Search protein sequence]
PRFLEYSTSECHFFNGTERVRYLDRYFHNQEENVRFDSDVGEFRAVTELG
RPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFTVQRRVHPKVTVYPS
KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWT
FQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAR
3D structure
PDB1a6a The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3.
ChainB
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y30 F47 P56 D57 Y60 W61 K71 R74 N77 Y78 H81 N82 V85 V86 Y26 F43 P52 D53 Y56 W57 K67 R70 N73 Y74 H77 N78 V81 V82
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:1a6a, PDBe:1a6a, PDBj:1a6a
PDBsum1a6a
PubMed7477400
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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