Structure of PDB 1a3q Chain B

Receptor sequence
>1a3qB (length=285) Species: 9606 (Homo sapiens) [Search protein sequence]
GPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYE
GPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNL
GVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMD
LSIVRLRFSAFLRSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRG
GDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTP
PYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYP
3D structure
PDB1a3q Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R52 R54 K221 R16 R18 K179
BS02 dna B Y55 C57 E58 K143 P223 Q254 Q284 Y19 C21 E22 K107 P181 Q212 Q242
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1a3q, PDBe:1a3q, PDBj:1a3q
PDBsum1a3q
PubMed9384586
UniProtQ00653|NFKB2_HUMAN Nuclear factor NF-kappa-B p100 subunit (Gene Name=NFKB2)

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