Structure of PDB 1a25 Chain B

Receptor sequence
>1a25B (length=132) Species: 10116 (Rattus norvegicus) [Search protein sequence]
ERRGRIYIQAHIDREVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKS
ESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFM
GSLSFGISELQKAGVDGWFKLLSQEEGEYFNV
3D structure
PDB1a25 Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.13: protein kinase C.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B D187 D193 D246 W247 D248 D31 D37 D90 W91 D92
BS02 CA B M186 D187 D246 D248 D254 M30 D31 D90 D92 D98
BS03 CA B D248 S251 R252 D254 D92 S95 R96 D98
BS04 PSE B Y195 K197 K209 K211 W245 N253 Y39 K41 K53 K55 W89 N97
External links
PDB RCSB:1a25, PDBe:1a25, PDBj:1a25
PDBsum1a25
PubMed9817842
UniProtP68403|KPCB_RAT Protein kinase C beta type (Gene Name=Prkcb)

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