Structure of PDB 1a1a Chain B

Receptor sequence
>1a1aB (length=102) Species: 9606 (Homo sapiens) [Search protein sequence]
AEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYSLSVSDFDNA
KGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTV
CP
3D structure
PDB1a1a Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B K155 I156 K8 I9
BS02 peptide B R158 R178 T182 S188 K203 H204 Y205 G239 R11 R31 T35 S41 K56 H57 Y58 G92
External links
PDB RCSB:1a1a, PDBe:1a1a, PDBj:1a1a
PDBsum1a1a
PubMed9174343
UniProtP12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

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