Structure of PDB 7ane Chain Ax

Receptor sequence

>7aneAx (length=167) Species: 5664 (Leishmania major)

HGKPASGHKVRTQHSRRWWMQSKAHHLTAVPHEEARSRPHFPAYTEDVDQ
PMVVPDGVCCFNCDKPIDGDDINSYVWVPSGNARVPTTQGYFFHVKCFKC
WNCKYRIIHNQFYSKDSRAWCLSCALGRDIRVPTRRWHTSYVNTHRTGSR
LTGQFFPRHRHQMEFLF

3D structure

• PDB: 7ane Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.
• Chain: Ax
• Resolution: 3.9 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Ax	H46 G47 K48 P49 A50 S51 H53 K54 V55 R56 T57 Q58 H59 S60 R61 W63 W64 Q66 S67 R81 R83 H85 N118 R151 I153 H154 R180 R181 Y186 L196	H1 G2 K3 P4 A5 S6 H8 K9 V10 R11 T12 Q13 H14 S15 R16 W18 W19 Q21 S22 R36 R38 H40 N73 R106 I108 H109 R135 R136 Y141 L151
BS02	ZN	Ax	C105 H139 C142	C60 H94 C97
BS03	ZN	Ax	C145 C148 C166 C169	C100 C103 C121 C124

Gene Ontology

Molecular Function

• GO:0046872 metal ion binding

External links

• PDB: RCSB:7ane, PDBe:7ane, PDBj:7ane
• PDBsum: 7ane
• PubMed: 33168716
• UniProt: Q4Q7T1