Structure of PDB 7o81 Chain Aw

Receptor sequence

>7o81Aw (length=141) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

GKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIV
LEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVL
VAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPR

3D structure

PDB

7o81 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.

Chain

Resolution

3.1 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Aw	G2 K3 C4 R5 G6 R8 T9 R11 H16 R17 R18 Q20 W22 H23 D24 K25 K28 T34 A35 L36 K37 A38 A44 S45 H46 A47 K48 E58 K60 Q61 N63 S64 A65 I66 R67 K68 K76 P86 N87 D88 G104 G106 R107 K108 H110 V112 G113 D114 I115 R119 K121 K124 S129 K137 K138	G1 K2 C3 R4 G5 R7 T8 R10 H15 R16 R17 Q19 W21 H22 D23 K24 K27 T33 A34 L35 K36 A37 A43 S44 H45 A46 K47 E57 K59 Q60 N62 S63 A64 I65 R66 K67 K75 P85 N86 D87 G103 G105 R106 K107 H109 V111 G112 D113 I114 R118 K120 K123 S128 K136 K137
BS02	rna	Aw	Q61 X62	Q60 X61

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005791	rough endoplasmic reticulum
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:7o81, PDBe:7o81, PDBj:7o81
PDBsum	7o81
PubMed	34029205
UniProt	G1SZ47\|RS23_RABIT Small ribosomal subunit protein uS12 (Gene Name=RPS23)