Structure of PDB 7mpj Chain Ao

Receptor sequence

>7mpjAo (length=105) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

VNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFG
GQTKPVFHKKAKTTKKVVLRLECVKCKTRAQLTLKRCKHFELGGEKKQKG
QALQF

3D structure

PDB

7mpj CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations.

Chain

Resolution

2.7 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	Ao	V2 N3 P5 R8 K9 T10 Y11 K13 K15 R18 K19 H20 Y28 A30 A33 F36 A37 Q38 G39 R41 R42 R45 K46 G49 F50 G52 Q53 K55 P56 V57 F58 H59 K60 K61 A62 K63 T65 K66 K67 V69 T79 R80 Q82 L83 T84 K86 R87 C88 K89 K97 K98 K100	V1 N2 P4 R7 K8 T9 Y10 K12 K14 R17 K18 H19 Y27 A29 A32 F35 A36 Q37 G38 R40 R41 R44 K45 G48 F49 G51 Q52 K54 P55 V56 F57 H58 K59 K60 A61 K62 T64 K65 K66 V68 T78 R79 Q81 L82 T83 K85 R86 C87 K88 K96 K97 K99
BS02	MG	Ao	K63 T65	K62 T64
BS03	ZN	Ao	C12 C17 C74	C11 C16 C73

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0008270	zinc ion binding

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0044391	ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:7mpj, PDBe:7mpj, PDBj:7mpj
PDBsum	7mpj
PubMed	35489333
UniProt	P0CX27\|RL44A_YEAST Large ribosomal subunit protein eL42A (Gene Name=RPL42A)