Structure of PDB 7ane Chain Ao

Receptor sequence

>7aneAo (length=275) Species: 5664 (Leishmania major) [Search protein sequence]

ASTAKGYMNRVMVYAHRRRKARYLAPKNAHVRSPLAHKMPEEYGNTWDPR
SGVEWHNRMRNRNHYRHWPWARWTDDPVRFHQDSVCHRTVSALSTVANNG
APEWDYYAEVGQAYETPSHFPLSYTAPFIYQYTAQCWSREDLQSYLERIE
QSSGLRTIADAASRREALYTWWHNAGMNVIPLGVLQHLELVSRDIVAQNA
RKSYRIEQHERGILRTPEMERYYALPHLRGPSMPVQLAQPSGKYPSGKFT
QMMEDVAIHPLQKPDARYKHNMYPA

3D structure

PDB

7ane Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.

Chain

Resolution

3.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Ao	A10 S11 A13 K14 M21 V22 A24 H25 R26 R27 R28 K29 R31 Y32 K36 N37 A38 H39 V40 R41 H65 R69 N70 R71 N72 R75 M261 V265 D274 R276 Y277 K278 H279 M281 Y282	A1 S2 A4 K5 M12 V13 A15 H16 R17 R18 R19 K20 R22 Y23 K27 N28 A29 H30 V31 R32 H56 R60 N61 R62 N63 R66 M252 V256 D265 R267 Y268 K269 H270 M272 Y273

External links

PDB	RCSB:7ane, PDBe:7ane, PDBj:7ane
PDBsum	7ane
PubMed	33168716
UniProt	Q4Q547

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