Structure of PDB 6p5k Chain Ao

Receptor sequence

>6p5kAo (length=104) Species: 9986 (Oryctolagus cuniculus)

VNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQ
TKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKG
QVIQ

3D structure

• PDB: 6p5k The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
• Chain: Ao
• Resolution: 3.1 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Ao	V2 N3 P5 R8 R9 T10 F11 K13 K17 H18 Y26 K28 G29 K30 D31 S32 Y34 A35 Q36 G37 R39 R40 R43 K44 G47 Y48 G50 Q51 T52 P54 I55 F56 R57 K58 A60 K61 T63 K64 K65 V67 K80 R81 M82 A84 K86 R87 C88 K89 K97 K98 K100	V1 N2 P4 R7 R8 T9 F10 K12 K16 H17 Y25 K27 G28 K29 D30 S31 Y33 A34 Q35 G36 R38 R39 R42 K43 G46 Y47 G49 Q50 T51 P53 I54 F55 R56 K57 A59 K60 T62 K63 K64 V66 K79 R80 M81 A83 K85 R86 C87 K88 K96 K97 K99

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6p5k, PDBe:6p5k, PDBj:6p5k
• PDBsum: 6p5k
• PubMed: 31609474
• UniProt: G1T040|RL36A_RABIT Large ribosomal subunit protein eL42 (Gene Name=RPL36A)