Structure of PDB 6p5j Chain Aj

Receptor sequence

>6p5jAj (length=86) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPK

3D structure

PDB

6p5j The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.

Chain

Resolution

3.1 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Aj	T2 K3 G4 T5 S6 S7 F8 G9 K10 R11 R12 N13 T15 H16 K25 H28 Q30 G35 K36 K42 R43 K44 R45 K46 Y47 N48 W49 K52 R55 R56 Y71 E80 G81	T1 K2 G3 T4 S5 S6 F7 G8 K9 R10 R11 N12 T14 H15 K24 H27 Q29 G34 K35 K41 R42 K43 R44 K45 Y46 N47 W48 K51 R54 R55 Y70 E79 G80
BS02	rna	Aj	R20 R21 C22 G23 K42 N57 T59 G62 R63 M64 R65 H66 L67 K68 V70 R72 F74 H76 F78 R79 E80 G81 T82 P84 K87	R19 R20 C21 G22 K41 N56 T58 G61 R62 M63 R64 H65 L66 K67 V69 R71 F73 H75 F77 R78 E79 G80 T81 P83 K86

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding
GO:0046872	metal ion binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:6p5j, PDBe:6p5j, PDBj:6p5j
PDBsum	6p5j
PubMed	31609474
UniProt	U3KPD5\|RL37_RABIT Large ribosomal subunit protein eL37 (Gene Name=RPL37)