Structure of PDB 8oin Chain Ag

Receptor sequence

>8oinAg (length=328) Species: 9823 (Sus scrofa) [Search protein sequence]

TVDFIKKQIEEFNIGKRHLANMMGEDPETFTQEDIDRAIAYLFPSGLFEK
RARPIMKHPEEIFPKQRAIQWGEDGRPFHFLFYTGKQSYYSLMHDTYGKL
LDVEKHHNQLRAKDLLAEKTKILKDPIGSRWLIKEELEEMLVEKLSDQDY
AQFIRLLERLSALPCGATEEDFVNRFRRSIPIQSKKQLIEPLQYDEQGMA
FSRGEGKRKTAKAEVVVYGQGSGRIDVNGVDYLLYFPVTQDREQLMFPLH
FLDRLGKHDMTCAVSGGGRSAQAGAVRLAMARALCSFVTEDEVEWMRQAG
LLTADPRVRERKKPGQEGARRKFTWKKR

3D structure

PDB

8oin Molecular basis of translation termination at noncanonical stop codons in human mitochondria.

Chain

Resolution

3.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Ag	F117 E118 Q217 R277 K278 V307 G337 R338 S339 R376 R378 E379 R380 K381 K382 P383 G384 A388 R389 R390 T393 W394 K395 K396 R397	F48 E49 Q148 R208 K209 V238 G268 R269 S270 R307 R309 E310 R311 K312 K313 P314 G315 A319 R320 R321 T324 W325 K326 K327 R328
BS02	rna	Ag	K396 R397	K327 R328

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005730	nucleolus
GO:0005739	mitochondrion
GO:0005763	mitochondrial small ribosomal subunit
GO:0005840	ribosome
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8oin, PDBe:8oin, PDBj:8oin
PDBsum	8oin
PubMed	37141370
UniProt	I3LU08

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