Structure of PDB 8ppl Chain Ae

Receptor sequence
>8pplAe (length=59) Species: 9606 (Homo sapiens) [Search protein sequence]
KVHGSLARAGKVRGQTPKVAKQEKKKKKTGRAKRRMQYNRRFVNVVPTFG
KKKGPNANS
3D structure
PDB8ppl Universal features of Nsp1-mediated translational shutdown by coronaviruses.
ChainAe
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Ae L6 R8 A9 K11 V12 Q15 T16 K21 Q22 K24 K25 K26 T29 G30 R31 K33 R34 R35 N39 R41 N44 G54 P55 N56 N58 S59 L6 R8 A9 K11 V12 Q15 T16 K21 Q22 K24 K25 K26 T29 G30 R31 K33 R34 R35 N39 R41 N44 G54 P55 N56 N58 S59
BS02 peptide Ae F49 K51 F49 K51
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0002227 innate immune response in mucosa
GO:0006412 translation
GO:0019731 antibacterial humoral response
GO:0050830 defense response to Gram-positive bacterium
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:8ppl, PDBe:8ppl, PDBj:8ppl
PDBsum8ppl
PubMed37802027
UniProtP62861|RS30_HUMAN Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein (Gene Name=FAU)

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