Structure of PDB 8oip Chain Ad

Receptor sequence

>8oipAd (length=343) Species: 9823 (Sus scrofa) [Search protein sequence]

SFFTKLTADELWKGALAESGAGARKGRGKRTKKKRRKDLNRGQIIGEGRH
GFLWPGLNIPLMRNGAVQTIAQRSKEDQEKVEADMVQQREEWDRRRKMKV
KRERGWSGNTWGGVSLGPPDPGPNGETYDDFDTRILEVRNVFNMTAKEGR
KRSVRVLVAVGNGKGAAGFAIGKATERADAFRKAKNRAVHYLHYIERYED
HTIYHDISLKFKRTHIKMKKQPRGYGLHCHRAIMTICRLIGIKDLYAKVS
GSVNMLNLTRGLFLGLSRQETHQQLADKKSLHVVEFREECGPLPIVVASP
QGALRKDPEPEDEVPDITLDWEDVKAAQGMKRSVWSGLKRAAT

3D structure

PDB

8oip Molecular basis of translation termination at noncanonical stop codons in human mitochondria.

Chain

Resolution

3.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Ad	T91 G101 G109 R114 R117 S194 G195 N196 R226 V228 F229 N230 M231 A233 K234 E235 R237 R242 I258 K260 R269 K270 K299 R300 H315 C316 H317 R318 A334 K335 S339 N341 R347 W408 R419 V421 W422 R427	T4 G14 G22 R27 R30 S107 G108 N109 R139 V141 F142 N143 M144 A146 K147 E148 R150 R155 I171 K173 R182 K183 K212 R213 H228 C229 H230 R231 A247 K248 S252 N254 R260 W321 R332 V334 W335 R340
BS02	rna	Ad	K112 R237	K25 R150

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8oip, PDBe:8oip, PDBj:8oip
PDBsum	8oip
PubMed	37141370
UniProt	F1SU66

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