Structure of PDB 8ic2 Chain Ac

Receptor sequence

>8ic2Ac (length=369) Species: 10090 (Mus musculus) [Search protein sequence]

HPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQIITGLFLAMHYTS
DTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSY
TFMETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSIGTTLV
EWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNNPTGL
NSDADKIPFHPYYTIKDILGILIMFLILMTLVLFFPDMLGDPDNYMPANP
LNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALMPFLHTSK
QRSLMFRPITQILYWILVANLLILTWIGGQPVEHPFIIIGQLASISYFSI
ILILMPISGIIEDKMLKLY

3D structure

PDB

8ic2 Respiratory complex CI:CIII2, type I, PERK -/- mouse under cold temperature

Chain

Resolution

6.3 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	HEM	Ac	Q44 I45 G48 L51 R80 H83 A87 A127 G130 P134 H182 F183 P186 F187	Q37 I38 G41 L44 R73 H76 A80 A120 G123 P127 H171 F172 P175 F176
BS02	HEM	Ac	W31 L37 L94 H97 V98 R100 S106 W113 G116 L119 H196 L200 S205 N206	W24 L30 L87 H90 V91 R93 S99 W106 G109 L112 H185 L189 S194 N195
BS03	U10	Ac	F121 M124 F128 I146 P270 Y278 L294	F114 M117 F121 I139 P259 Y267 L283
BS04	UQ6	Ac	S17 F18 L21 S35 G38 M42 F220	S10 F11 L14 S28 G31 M35 F209

External links

PDB	RCSB:8ic2, PDBe:8ic2, PDBj:8ic2
PDBsum	8ic2
PubMed
UniProt	P00158\|CYB_MOUSE Cytochrome b (Gene Name=Mt-Cyb)

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