Structure of PDB 8ib4 Chain Ac

Receptor sequence

>8ib4Ac (length=373) Species: 10090 (Mus musculus) [Search protein sequence]

HPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQIITGLFLAMHYTS
DTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSY
TFMETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIG
TTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNN
PTGLNSDADKIPFHPYYTIKDILGILIMFLILMTLVLFFPDMLGDPDNYM
PANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALMPFL
HTSKQRSLMFRPITQILYWILVANLLILTWIGGQPVEHPFIIIGQLASIS
YFSIILILMPISGIIEDKMLKLY

3D structure

PDB

8ib4 Respiratory complex CI:CIII2, type IA, Wild type mouse under cold temperature

Chain

Resolution

4.3 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	HEM	Ac	Q44 I45 G48 L51 R80 H83 A87 A127 G130 L133 H182 F183 P186 F187	Q37 I38 G41 L44 R73 H76 A80 A120 G123 L126 H175 F176 P179 F180
BS02	HEM	Ac	W31 G34 L37 L94 H97 V98 R100 S106 T112 G116 H196 L200 S205 N206	W24 G27 L30 L87 H90 V91 R93 S99 T105 G109 H189 L193 S198 N199
BS03	U10	Ac	A125 F128 M129 I146 I164 F178 F181 L185 F274	A118 F121 M122 I139 I157 F171 F174 L178 F267
BS04	UQ6	Ac	F18 L21 S35 M42 L197 F220	F11 L14 S28 M35 L190 F213

External links

PDB	RCSB:8ib4, PDBe:8ib4, PDBj:8ib4
PDBsum	8ib4
PubMed
UniProt	P00158\|CYB_MOUSE Cytochrome b (Gene Name=Mt-Cyb)

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