Structure of PDB 8iar Chain Ac

Receptor sequence

>8iarAc (length=373) Species: 10090 (Mus musculus) [Search protein sequence]

HPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQIITGLFLAMHYTS
DTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSY
TFMETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIG
TTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNN
PTGLNSDADKIPFHPYYTIKDILGILIMFLILMTLVLFFPDMLGDPDNYM
PANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALMPFL
HTSKQRSLMFRPITQILYWILVANLLILTWIGGQPVEHPFIIIGQLASIS
YFSIILILMPISGIIEDKMLKLY

3D structure

PDB

8iar Respiratory complex CIII2, focus-refined of type I, Wild type mouse under thermoneutral temperature

Chain

Resolution

3.4 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	HEM	Ac	Q44 G48 L51 Y55 H83 G130 P134 H182 F183 P186 F187	Q37 G41 L44 Y48 H76 G123 P127 H175 F176 P179 F180
BS02	HEM	Ac	W31 L37 L94 H97 V98 R100 S106 W113 G116 H196 L197 L200 S205 N206	W24 L30 L87 H90 V91 R93 S99 W106 G109 H189 L190 L193 S198 N199
BS03	U10	Ac	F121 M124 A125 F128 I146 P270 Y278 L294	F114 M117 A118 F121 I139 P263 Y271 L287
BS04	UQ6	Ac	S17 F18 L21 M42 L197 H201 F220	S10 F11 L14 M35 L190 H194 F213

External links

PDB	RCSB:8iar, PDBe:8iar, PDBj:8iar
PDBsum	8iar
PubMed
UniProt	P00158\|CYB_MOUSE Cytochrome b (Gene Name=Mt-Cyb)

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