Structure of PDB 5aj0 Chain Ab

Receptor sequence

>5aj0Ab (length=68) Species: 9606 (Homo sapiens)

AKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNK
KGLKKMQANNAKAMSARA

3D structure

• PDB: 5aj0 Structural Snapshots of Actively Translating Human Ribosomes
• Chain: Ab
• Resolution: 3.5 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Ab	A2 S4 K5 N6 H7 T8 T9 H10 N11 Q12 S13 R14 K15 H17 R18 G20 R25 Q27 R28 Y29 E30 L32 D36 K38 F39 R41 N42 R44 F45 K47 H49 N50 G53 L54 M57 Q58 N61 M65	A1 S3 K4 N5 H6 T7 T8 H9 N10 Q11 S12 R13 K14 H16 R17 G19 R24 Q26 R27 Y28 E29 L31 D35 K37 F38 R40 N41 R43 F44 K46 H48 N49 G52 L53 M56 Q57 N60 M64

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0008201 heparin binding
• GO:0045296 cadherin binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0007566 embryo implantation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0016020 membrane
• GO:0022625 cytosolic large ribosomal subunit
• GO:0022626 cytosolic ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5aj0, PDBe:5aj0, PDBj:5aj0
• PDBsum: 5aj0
• PubMed: 25957688
• UniProt: P47914|RL29_HUMAN Large ribosomal subunit protein eL29 (Gene Name=RPL29)