Structure of PDB 5aj0 Chain AZ

Receptor sequence
>5aj0AZ (length=134) Species: 9606 (Homo sapiens) [Search protein sequence]
KFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRK
VTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSVDIPLDKTVVNKDVFR
DPALKRKARREAKVKFEERYKTGKNKWFFQKLRF
3D structure
PDB5aj0 Structural Snapshots of Actively Translating Human Ribosomes
ChainAZ
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna AZ A15 G16 R17 Y38 R51 T54 K59 R65 K67 K69 V74 N76 H79 K107 R108 R111 R112 K115 K133 R135 F136 A13 G14 R15 Y36 R49 T52 K57 R63 K65 K67 V72 N74 H77 K105 R106 R109 R110 K113 K131 R133 F134
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006364 rRNA processing
GO:0006412 translation
GO:1904044 response to aldosterone
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0045202 synapse
GO:0070062 extracellular exosome
GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5aj0, PDBe:5aj0, PDBj:5aj0
PDBsum5aj0
PubMed25957688
UniProtP61353|RL27_HUMAN Large ribosomal subunit protein eL27 (Gene Name=RPL27)

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