Structure of PDB 4v4s Chain AY

Receptor sequence
>4v4sAY (length=365) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MDLERLAQRLEGLRGYLDIPQKETRLKELERRLEDPSLWNDPEAARKVSQ
EAARLRRTVDTFRSLESDLQGLLELMEELPAEEREALKPELEEAAKKLDE
LYHQTLLNFPHAEKNAILTIQPGAGGTEACDWAEMLLRMYTRFAERQGFQ
VEVVDLTPGPEAGIDYAQILVKGENAYGLLSPEAGVHRLVRPSPFDASGR
RHTSFAGVEVIPEVDEEVEVVLKPEELRIDVMRASGPGGQGVNTTDSAVR
VVHLPTGITVTCQTTRSQIKNKELALKILKARLYELERKKREEELKALRG
EVRPIEWGSQIRSYVLDKNYVKDHRTGLMRHDPENVLDGDLMDLIWAGLE
WKAGRRQGTEEVEAE
3D structure
PDB4v4s Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
ChainAY
Resolution6.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna AY M1 A124 M1 A124
BS02 rna AY R233 A234 S235 P237 G238 T244 T245 T261 R233 A234 S235 P237 G238 T244 T245 T261
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0006415 translational termination
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4v4s, PDBe:4v4s, PDBj:4v4s
PDBsum4v4s
PubMed16377566
UniProtQ5SM01|RF2_THET8 Peptide chain release factor RF2 (Gene Name=prfB)

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