Structure of PDB 8ois Chain AV

Receptor sequence
>8oisAV (length=362) Species: 9606 (Homo sapiens) [Search protein sequence]
LLSSAYVDSHKWEAREKEHYCLADLASLMDKTFERKLPVSSLTISRLIDN
ISSREEIDHAEYYLYKFRHSPNCWYLRNWTIHTWIRQCLKYDAQDKALYT
LVNKVQYGIFPDNFTFNLLMDSFIKKENYKDALSVVFEVMMQEAFEVPST
QLLSLYVLFHCLAKKTDFSWEEERNFGASLLLPGLKQKNSVGFSSQLYGY
ALLGKVELQQGLRAVYHNMPLIWKPGYLDRALQVMEKVAASPEDIKLCRE
ALDVLGAVLKALTSAEKLVEQLDIEETEQSKLPQYLERFKALHSKLQALG
KIESEGLLSLTTQLVKEKLSTCEAEDIATYEQNLQQWHLDLVQLIQREQQ
QREQAKQEYQAQ
3D structure
PDB8ois Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
ChainAV
Resolution3.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide AV C49 H87 Y90 Y93 C21 H59 Y62 Y65
BS02 rna AV K64 L65 P66 S68 S69 N100 W102 Y103 R105 R392 Q396 Q407 K36 L37 P38 S40 S41 N72 W74 Y75 R77 R347 Q351 Q362
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0097177 mitochondrial ribosome binding
Biological Process
GO:0006417 regulation of translation
GO:0008283 cell population proliferation
GO:0032543 mitochondrial translation
GO:0070131 positive regulation of mitochondrial translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ois, PDBe:8ois, PDBj:8ois
PDBsum8ois
PubMed37141370
UniProtQ92552|RT27_HUMAN Small ribosomal subunit protein mS27 (Gene Name=MRPS27)

[Back to BioLiP]