Structure of PDB 6p5n Chain AT

Receptor sequence

>6p5nAT (length=159) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

TNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKG
MPHKCYHGKTGRVYNVTQHAVGIVVNKQVKGKILAKRINVRIEHIKHSKS
RDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELL
EPIPYEFMA

3D structure

PDB

6p5n The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.

Chain

Resolution

3.2 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	AT	T2 N3 T4 K5 G6 R8 R9 R12 Y13 M14 S16 F19 H22 G23 K35 K36 D41 K43 T47 Q49 G51 H54 K55 Y57 H58 G59 K60 T61 T68 Q69 H70 N77 K78 V80 K81 K87 R88 N90 R92 K97 K100 R102 S104 F105 R108 K116 W125 V126 L128 K129 R130 F140 R142	T1 N2 T3 K4 G5 R7 R8 R11 Y12 M13 S15 F18 H21 G22 K34 K35 D40 K42 T46 Q48 G50 H53 K54 Y56 H57 G58 K59 T60 T67 Q68 H69 N76 K77 V79 K80 K86 R87 N89 R91 K96 K99 R101 S103 F104 R107 K115 W124 V125 L127 K128 R129 F139 R141
BS02	rna	AT	R20 P26 A28	R19 P25 A27

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6p5n, PDBe:6p5n, PDBj:6p5n
PDBsum	6p5n
PubMed	31609474
UniProt	G1SHQ2\|RL21_RABIT Large ribosomal subunit protein eL21 (Gene Name=RPL21)

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