Structure of PDB 8wq2 Chain AS5P

Receptor sequence

>8wq2AS5P (length=204) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence]

EDWKPRTKVGQLIKEGKINSMKELFERNLPIVEPEIVDVLLPKLRYDIVD
IGIVQKQTDAGELSRYKVLIVMGNMDGYISYGTGKAKQLRVAIQKAIRDA
KMRIIPVRRGCGSWECTCGESHSLPFIVSGKAGSVEVTLLPAPKGTGLVV
GSVLKTFLSLAGLKDVWSRTKGSTYTHENFIKAAYIALYNTYRFVTPVDW
GRMK

3D structure

PDB

8wq2 Structural basis of translation inhibition by a valine tRNA-derived fragment

Chain

AS5P

Resolution

4.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	AS5P	Q70 K71 Q72 T73 D74 R113 K146 G148 S149 V164 V165 G166 S167 W182 S183 R184 T185 S188 T189 Y190 H192 N194 K197	Q55 K56 Q57 T58 D59 R98 K131 G133 S134 V149 V150 G151 S152 W167 S168 R169 T170 S173 T174 Y175 H177 N179 K182
BS02	UNK	AS5P	K37 K219	K22 K204
BS03	UNK	AS5P	N43 P121	N28 P106

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8wq2, PDBe:8wq2, PDBj:8wq2
PDBsum	8wq2
PubMed	38599770
UniProt	O05641\|RS5_SULAC Small ribosomal subunit protein uS5 (Gene Name=rps5)

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