Structure of PDB 8hkz Chain AS4E

Receptor sequence

>8hkzAS4E (length=240) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence]

VHITRFEAPWFLKVGKKEYKWIIRSRAGPHKIQESVPLAILLKYYLKAVD
TTREAKRIIFDGKVLVDGKVRRDYKYPVGLMDVVEIPSADLRVRIIPDNV
RYLTTINISREDAKYKFVRIMNKTTLKSGVLQLNLEDGRNILLKGEELSQ
YNLPTLTTLKIELPEQKITTAYTIKEGVYAMIIGGRNAGLHGKISKIQLA
KYKRIKYSLVTLEGKDGSTFQTNLINVMAIGENEADSNLG

3D structure

PDB

8hkz Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome.

Chain

AS4E

Resolution

4.78 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	AS4E	V1 H2 F6 E7 K13 K17 Y19 W21 I22 I23 R24 R26 A27 G28 P29 K31 I32 R53 F60 R71 Y76 Y102 N122 K123 T125 L126 K127 S128 G129 L131 N134 G138 R139 N140 E165 Q166 G185 R186 K201 K203 R204 K206 F220 Q221	V1 H2 F6 E7 K13 K17 Y19 W21 I22 I23 R24 R26 A27 G28 P29 K31 I32 R53 F60 R71 Y76 Y102 N122 K123 T125 L126 K127 S128 G129 L131 N134 G138 R139 N140 E165 Q166 G185 R186 K201 K203 R204 K206 F220 Q221

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8hkz, PDBe:8hkz, PDBj:8hkz
PDBsum	8hkz
PubMed	37604686
UniProt	O05634\|RS4E_SULAC Small ribosomal subunit protein eS4 (Gene Name=rps4e)

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