Structure of PDB 9bdn Chain AS23

Receptor sequence

>9bdnAS23 (length=141) Species: 9986 (Oryctolagus cuniculus)

GKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIV
LEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVL
VAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPR

3D structure

• PDB: 9bdn Structural mechanism of angiogenin activation by the ribosome.
• Chain: AS23
• Resolution: 3.1 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	AS23	G2 K3 C4 R5 G6 L7 R8 T9 R11 K12 R17 R18 Q20 W22 H23 D24 K28 L36 A44 S45 H46 A47 K48 Q61 N63 S64 A65 I66 R67 K68 I75 K76 N87 D88 G104 G106 R107 K108 H110 V112 G113 D114 R119 S129 L131 Y134 K137	G1 K2 C3 R4 G5 L6 R7 T8 R10 K11 R16 R17 Q19 W21 H22 D23 K27 L35 A43 S44 H45 A46 K47 Q60 N62 S63 A64 I65 R66 K67 I74 K75 N86 D87 G103 G105 R106 K107 H109 V111 G112 D113 R118 S128 L130 Y133 K136

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005783 endoplasmic reticulum
• GO:0005791 rough endoplasmic reticulum
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022626 cytosolic ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:9bdn, PDBe:9bdn, PDBj:9bdn
• PDBsum: 9bdn
• PubMed: 38718836
• UniProt: G1SZ47|RS23_RABIT Small ribosomal subunit protein uS12 (Gene Name=RPS23)