Structure of PDB 9bdp Chain AS16

Receptor sequence

>9bdpAS16 (length=142) Species: 9986 (Oryctolagus cuniculus)

GPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEP
VLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEAS
KKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR

3D structure

• PDB: 9bdp Structural mechanism of angiogenin activation by the ribosome.
• Chain: AS16
• Resolution: 3.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	AS16	Q11 V12 F13 R15 K17 T18 H24 K33 N35 R37 E43 R69 R71 K73 G74 G75 G76 H77 V78 A79 Q80 V121 R125 C127 E128 S129 K130 K131 F132 G133 G136 A137 R138 A139 Y141 Q142 K143 S144 Y145 R146	Q7 V8 F9 R11 K13 T14 H20 K29 N31 R33 E39 R65 R67 K69 G70 G71 G72 H73 V74 A75 Q76 V117 R121 C123 E124 S125 K126 K127 F128 G129 G132 A133 R134 A135 Y137 Q138 K139 S140 Y141 R142

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
• GO:0006364 rRNA processing
• GO:0042274 ribosomal small subunit biogenesis
• GO:1990830 cellular response to leukemia inhibitory factor

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022626 cytosolic ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:0032040 small-subunit processome
• GO:0045202 synapse
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:9bdp, PDBe:9bdp, PDBj:9bdp
• PDBsum: 9bdp
• PubMed: 38718836
• UniProt: G1SGX4|RS16_RABIT Small ribosomal subunit protein uS9 (Gene Name=RPS16)