Structure of PDB 9bdn Chain AS08

Receptor sequence

>9bdnAS08 (length=206) Species: 9986 (Oryctolagus cuniculus)

GISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGG
NKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCI
VLIDSTPYRQWYESHYALPLGRKKGAKLTPEEEEILNKKRSKKIQKKYDE
RKKNAKISSLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRK
IKARKG

3D structure

• PDB: 9bdn Structural mechanism of angiogenin activation by the ribosome.
• Chain: AS08
• Resolution: 3.1 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	AS08	G2 R5 D6 N7 H9 K10 R11 R12 K13 T14 K19 Y21 H22 K23 K24 R25 K26 Y27 L29 G30 R31 R41 R42 I43 H44 T45 R47 V48 R49 G50 G51 N52 K54 Y55 R56 R59 N64 S66 T73 S86 V97 K98 N99 R141 S142 K143 K144 K147 A176 G180 Q181 G183 R184 D186	G1 R4 D5 N6 H8 K9 R10 R11 K12 T13 K18 Y20 H21 K22 K23 R24 K25 Y26 L28 G29 R30 R40 R41 I42 H43 T44 R46 V47 R48 G49 G50 N51 K53 Y54 R55 R58 N63 S65 T72 S85 V96 K97 N98 R140 S141 K142 K143 K146 A175 G179 Q180 G182 R183 D185
BS02	rna	AS08	R92 K206	R91 K205

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0016020 membrane
• GO:0022626 cytosolic ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:9bdn, PDBe:9bdn, PDBj:9bdn
• PDBsum: 9bdn
• PubMed: 38718836
• UniProt: G1TJW1|RS8_RABIT Small ribosomal subunit protein eS8 (Gene Name=RPS8)