Structure of PDB 8ove Chain AS

Receptor sequence

>8oveAS (length=140) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]

TKTNGQHAARKLVRLRRKNRWADKGWKKSHTFVAQKANPFGGSSHAKGIV
LEKIGVGAKQPNSAIRKCVRVQLIKNDKKIIAFVPNDGCLHFIEENDEVL
VSGFGRSGHAVGDIPGVRFKIVKVSSVGLYALYRQKKEKP

3D structure

PDB

8ove A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei.

Chain

Resolution

2.6 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	AS	T2 K3 T4 N5 G6 H8 R11 K12 R15 R17 N20 W22 A23 D24 K28 S30 F33 S45 H46 K48 N63 S64 A65 R67 K68 N87 D88 G104 G106 R107 S108 D114 R119 K124 K137	T1 K2 T3 N4 G5 H7 R10 K11 R14 R16 N19 W21 A22 D23 K27 S29 F32 S44 H45 K47 N62 S63 A64 R66 K67 N86 D87 G103 G105 R106 S107 D113 R118 K123 K136

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005730	nucleolus
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links