Structure of PDB 4v9b Chain AR

Receptor sequence
>4v9bAR (length=88) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHH
SHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG
3D structure
PDB4v9b Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis.
ChainAR
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna AR P2 K5 K8 D21 T22 G23 S24 T25 Q28 L31 R35 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 M58 M59 R64 R65 R68 Y69 R72 P1 K4 K7 D20 T21 G22 S23 T24 Q27 L30 R34 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 M57 M58 R63 R64 R67 Y68 R71
BS02 rna AR S40 H53 L56 G89 S39 H52 L55 G88
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:4v9b, PDBe:4v9b, PDBj:4v9b
PDBsum4v9b
PubMed23431179
UniProtQ5SJ76|RS15_THET8 Small ribosomal subunit protein uS15 (Gene Name=rpsO)

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