Structure of PDB 8ove Chain AP

Receptor sequence
>8oveAP (length=220) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
EWVPCTKLGRLVKDQKITSLEEIFLFSMPIKEHQIVDQLIREGDLRDEMM
LVFPVQKATSAGQRTRFKAFNVVGDGNGHIGVGARVGKEVSLAIRASMIA
AKLSIVPVRRGYWGNKIGEPHTIPIKVTGKCGSVAVRLIPAPRGAGIVAA
PVPKKILEFAGVEDVYTSSCGKTRTRGNFIMATFYALRKTYGFLTPDLWA
ETEVSRDPTDEHSEFLSMGR
3D structure
PDB8ove A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei.
ChainAP
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna AP Q97 K98 A99 T100 R107 K109 K129 T169 S174 R178 A190 A191 Y207 T208 C211 R215 T216 Q56 K57 A58 T59 R66 K68 K88 T128 S133 R137 A149 A150 Y166 T167 C170 R174 T175
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ove, PDBe:8ove, PDBj:8ove
PDBsum8ove
PubMed37985661
UniProtQ388D3

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