Structure of PDB 7tor Chain AL42

Receptor sequence

>7torAL42 (length=104) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

VNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQ
TKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKG
QVIQ

3D structure

PDB

7tor Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.

Chain

AL42

Resolution

2.9 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	AL42	V2 N3 P5 R8 R9 T10 F11 K13 K17 H18 Y26 K28 D31 S32 Y34 A35 Q36 G37 R39 R40 R43 K44 G47 Y48 G50 Q51 T52 P54 I55 F56 K58 K59 A60 K61 T63 K64 K65 K80 R81 K86 C88 K89 K97 K98 K100	V1 N2 P4 R7 R8 T9 F10 K12 K16 H17 Y25 K27 D30 S31 Y33 A34 Q35 G36 R38 R39 R42 K43 G46 Y47 G49 Q50 T51 P53 I54 F55 K57 K58 A59 K60 T62 K63 K64 K79 R80 K85 C87 K88 K96 K97 K99
BS02	rna	AL42	Y41 K53 P54 I55 F56	Y40 K52 P53 I54 F55
BS03	rna	AL42	I104 Q105	I103 Q104
BS04	ZN	AL42	C12 C72 C77	C11 C71 C76

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome

External links