Structure of PDB 7top Chain AL27

Receptor sequence
>7topAL27 (length=135) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
AKFLKAGKVAVVVRGRYAGKKVVIVKPHDEGSKSHPFGHALVAGIERYPL
KVTKKHGAKKVAKRTKIKPFIKVVNYNHLLPTRYTLDVEAFKSVVSTETF
EQPSQREEAKKVVKKAFEERHQAGKNQWFFSKLRF
3D structure
PDB7top Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
ChainAL27
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna AL27 R15 G16 R17 H36 F38 R48 K52 T54 K55 K56 G58 K61 K64 R65 K67 K69 K73 V74 N76 H79 R107 K112 K115 K133 R135 F136 R14 G15 R16 H35 F37 R47 K51 T53 K54 K55 G57 K60 K63 R64 K66 K68 K72 V73 N75 H78 R106 K111 K114 K132 R134 F135
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:7top, PDBe:7top, PDBj:7top
PDBsum7top
PubMed35589706
UniProtP0C2H6|RL27A_YEAST Large ribosomal subunit protein eL27A (Gene Name=RPL27A)

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