Structure of PDB 9bdp Chain AL23

Receptor sequence
>9bdpAL23 (length=131) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]
SGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGD
MVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNK
GEMKGSAITGPVAKECADLWPRIASNAGSIA
3D structure
PDB9bdp Structural mechanism of angiogenin activation by the ribosome.
ChainAL23
Resolution3.7 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna AL23 K69 P70 K60 P61
BS02 rna AL23 S10 A12 K13 F14 R15 S17 G19 P21 A24 V25 I40 V42 K43 G44 I45 K46 R48 L49 N50 R51 L52 T64 K74 V76 R85 K86 F95 N101 S1 A3 K4 F5 R6 S8 G10 P12 A15 V16 I31 V33 K34 G35 I36 K37 R39 L40 N41 R42 L43 T55 K65 V67 R76 K77 F86 N92
Gene Ontology
Molecular Function
GO:0001223 transcription coactivator binding
GO:0003735 structural constituent of ribosome
GO:0031625 ubiquitin protein ligase binding
GO:0070180 large ribosomal subunit rRNA binding
GO:1990948 ubiquitin ligase inhibitor activity
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0032986 protein-DNA complex disassembly
GO:0050821 protein stabilization
GO:0070314 G1 to G0 transition
GO:0072717 cellular response to actinomycin D
GO:1901798 positive regulation of signal transduction by p53 class mediator
GO:1903450 regulation of G1 to G0 transition
GO:1904667 negative regulation of ubiquitin protein ligase activity
GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0032991 protein-containing complex
GO:0045202 synapse
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:9bdp, PDBe:9bdp, PDBj:9bdp
PDBsum9bdp
PubMed38718836
UniProtG1T6D1|RL23_RABIT Large ribosomal subunit protein uL14 (Gene Name=RPL23)

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