Structure of PDB 9bdp Chain AL19

Receptor sequence

>9bdpAL19 (length=180) Species: 9986 (Oryctolagus cuniculus)

SMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLII
RKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRI
LRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKAR
KKLLADQAEARRSKTKEARKRREERLQAKK

3D structure

• PDB: 9bdp Structural mechanism of angiogenin activation by the ribosome.
• Chain: AL19
• Resolution: 3.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	AL19	R163 K165 R172 R173 R176	R162 K164 R171 R172 R175
BS02	rna	AL19	M3 L4 R5 K8 R9 L10 G18 K19 K20 K21 W23 L24 P26 R38 Q39 R42 K43 K46 T56 V57 H58 S59 R60 A61 R62 C63 R64 R70 R71 R74 I78 G79 K80 R81 K82 G83 T84 A85 A87 R88 P90 K92 W95 M96 R97 R100 R103 R107 R108 R110 R117 H118 Y120 H121 Y124 L125 K128 G129 N130 K135	M2 L3 R4 K7 R8 L9 G17 K18 K19 K20 W22 L23 P25 R37 Q38 R41 K42 K45 T55 V56 H57 S58 R59 A60 R61 C62 R63 R69 R70 R73 I77 G78 K79 R80 K81 G82 T83 A84 A86 R87 P89 K91 W94 M95 R96 R99 R102 R106 R107 R109 R116 H117 Y119 H120 Y123 L124 K127 G128 N129 K134

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:9bdp, PDBe:9bdp, PDBj:9bdp
• PDBsum: 9bdp
• PubMed: 38718836
• UniProt: G1TYL6|RL19_RABIT Large ribosomal subunit protein eL19 (Gene Name=RPL19)